In vitroactivities of posaconazole, ravuconazole, terbinafine, itraconazole and fluconazole against dermatophyte, yeast and non-dermatophyte species
نویسندگان
چکیده
منابع مشابه
In vitro activity of terbinafine against medically important non-dermatophyte species of filamentous fungi.
OBJECTIVES The activity in vitro of terbinafine against 442 clinical isolates of several species of filamentous fungi was analysed. METHODS A broth microdilution test was carried out following the National Committee for Clinical Laboratory Standards reference method, with modifications described previously. RESULTS The geometric mean (GM) of MICs of terbinafine for non-Aspergillus fumigatus...
متن کاملProfile of Dermatophyte and Non Dermatophyte Fungi in Patients Suspected of Dermatophytosis
Fungal infections of hair, nail and skin are common worldwide and continue to increase. The present study was undertaken to determine the prevalence of dermatophytosis, isolation rates and the profile of fungi associated with dermatophytosis. Samples were collected from 305 patients and a portion of each sample was examined microscopically and the remaining portion was cultured on to plates of ...
متن کاملShort term treatment of dermatophyte onychomycosis with terbinafine.
OBJECTIVE To evaluate the effect of short term treatment with terbinafine on dermatophytosis. DESIGN Multicentre, randomised, double blind placebo controlled trial of 250 mg/day terbinafine for 12 weeks in dermatophyte onychomycosis. SETTING Eight dermatology centres in the United Kingdom. PATIENTS 112 patients (mean age 44, range 19-78), 99 with mycologically proved toenail infections an...
متن کاملModel systems for the study of dermatophyte and non-dermatophyte invasion of human keratin
Both dermatophyte and non-dermatophyte fungi can colonise and invade the keratin of skin, nail and hair. The fungal morphological forms that adhere to these keratinaceous substrates are most probably arthroconidia and hyphal fragments in association with exfoliated corneocytes. Towards a greater understanding of the ability of fungi to utilise keratin we have developed a series of experimetal m...
متن کاملItraconazole pulse therapy for dermatophyte onychomycosis in children.
BACKGROUND Onychomycosis, or fungal infection of the nail, can occur in prepubertal children. However, its diagnosis is often missed or the condition is inappropriately treated with topical medication. Griseofulvin has been the therapy of choice, but even long-term treatment is associated with a poor cure rate and high rate of relapse. Trials with adult patients have shown that itraconazole pul...
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ژورنال
عنوان ژورنال: Medical Mycology
سال: 2005
ISSN: 1369-3786,1460-2709
DOI: 10.1080/13693780410001731583